import os
[docs]class SilentNetwork:
description = "A base, silent network with mild odor input and all synapses blocked"
@property
def name(self):
return self.__class__.__name__
rnd_seed = 0
slice_dir = os.path.join('olfactorybulb', 'slices')
slice_name = "DorsalColumnSlice"
sim_dt = 1 / 10.0
recording_period = 1 / 10.0 # ms
tstop = 800.1 # ms
# GJs disabled
gap_juction_gmax = {
"MC": 0,
"TC": 0,
}
# Disable excitatory and inhibitory syns
synapse_properties = {
"AmpaNmdaSyn": {
'gmax': 0,
'ltpinvl': 0, # Disable plasticity
'ltdinvl': 0
},
"GabaSyn": {
'gmax': 0,
'tau2': 100,
'ltpinvl': 0, # Disable plasticity
'ltdinvl': 0
}
}
# Mild odor input spikes
input_odors = {
0: {"name": "Apple", "rel_conc": 0.1},
200: {"name": "Apple", "rel_conc": 0.2},
400: {"name": "Apple", "rel_conc": 0.2},
600: {"name": "Apple", "rel_conc": 0.2},
800: {"name": "Apple", "rel_conc": 0.2},
1000: {"name": "Apple", "rel_conc": 0.2},
1200: {"name": "Apple", "rel_conc": 0.2},
1400: {"name": "Apple", "rel_conc": 0.2},
1600: {"name": "Apple", "rel_conc": 0.2},
1800: {"name": "Apple", "rel_conc": 0.2},
}
# From Manabe & Mori (2013) fast: 100-150ms, slow: 150 ms
inhale_duration = 125 # ms
# ORN firing rate
max_firing_rate = 150 # Hz from Duchamp-Viret et. al. (2000)
# Gilra Bhalla (2016)
input_syn_tau1 = 6
input_syn_tau2 = 12
# MC input disabled
mc_input_delay = 50
mc_input_weight = 0
# TC input disabled
tc_input_delay = 0
tc_input_weight = 0
# LFP electrode
# Inside dorsal Granule Layer
# Approximaly to where it was located in Manabe & Mori (2013)
# In adult male Long-Evans rat:
# 8.0 mm anterior to the bregma
# 1.3 mm lateral to the midline
# 2.5 mm from the skull surface
lfp_electrode_location = [116, 1078, -61]
record_from_somas = ['MC', 'TC', 'GC']
[docs]class ParameterSetBase(SilentNetwork):
pass